The 30-year-old Joanne singer will perform on the October 22 episode, which will be hosted by Tom Hanks.
Gaga has previously appeared on the sketch comedy series three other times. She was a musical guest in 2009 and 2011 and she pulled double duty as host and performer in 2013.
Lady Gaga Will Be SNL's Musical Guest with Host Tom Hanks!
Source: Just Jared